The present research was carried out with the aim of analyzing the effectiveness of the cooperative companies' performance from a strategic orientation with an emphasis on intellectual competence and innovation in the city of Mashhad. The current research is applied in terms of purpose and descriptive-survey in terms of data collection. The statistical population of this research is the members of the board of directors of cooperative companies in Razavi Khorasan province in number (7555 people). The sample size was determined based on Klein's proposed method and using a non-random method available to 240 people. The tool of data collection in this research is a standard questionnaire, which was used to verify the reliability of the questionnaire using Cronbach's alpha, and for the validity of the questionnaire, confirmatory factor analysis was used. In addition, divergent validity was also confirmed, to analyze the data by structural equation method and using smart pls software. Bootstrapping technique was used to investigate the role of mediating variables. The results indicate that the tendency to entrepreneurship has a significant effect on the performance of cooperative companies in Razavi Khorasan province. Also, orientation towards the market has a significant effect on the performance of cooperative companies in Razavi Khorasan province. Tendency to entrepreneurship has a significant effect on intellectual competences in cooperative companies. In addition, market orientation has a significant effect on knowledge competencies in cooperative companies. Knowledge competence through innovation affects the performance of cooperative companies. The type of cooperative company moderates the effect of entrepreneurial orientation and market orientation on the performance of cooperative companies in Razavi Khorasan province.